LioniX is world leader in IO sensing systems, ranging from fluorescence based, through absorption based, to interference based sensing geometries. LioniX combines Silicon and fused silica substrates in their microfluidics designs to provide the most a cost effective solution. In the case of using Silicon as substrate, PIN Si-detectors and even Si-based lightsources can be integrated in the substrate, allowing a broad range op applications.
Examples of integrated optical sensors, suitable for hybrid or monolithic combination with microfluidic systems, are based on:
- Changes in the fluorescence
- Refractive index change
- Absorption properties of the fluid
A good example of opto-fluidics as educational tool is the complete opto-fluidic analysis system for Saxion University of Applied Sciences in Enschede. The system is designed by LioniX, used in the bachelor program “Nanotechnology” and enables an easy accessible method for acquiring deeper insight in integrated optics and micro-fluidics. The system combines the LABTRIX micro reactor from ChemtriX BV with the Hyperion laserbox of XiO Photonics and at its core a fused silica based opto-fluidic microchip manufactured by LioniX. The integrated microchip enables online monitoring, and therefore direct optimization of the micro reactor product using absorption based evanescent field detection.
The Hyperion uses an Integrated Laser Beam Combiner (ILBC) to combine 3 different wavelengths (488, 532, 635 nm) into a single output fiber. This allows analysis of the micro reactor substance inside the opto-fluidic microchip using a wide range of wavelengths.
Laser beam combining for optical microscopy is a promising visible light application enabled by compact photonic chips.